一、基本信息
姓 名:李晨
性 别:男
學曆/學位:研究生/理學博士,美國克利夫蘭醫學中心博士後
職務職稱:生物工程系主任,碩士生導師,博士生導師,副教授
所在部門:bevictor伟德官网生物工程系(D座1306室,1320室)
通訊地址:河北省保定市樂凱南大街2596号bevictor伟德官网生物工程系
郵政編碼:071001
聯系電話:+86-0312-7528423 (工作)
電子郵箱:lichen@hebau.edu.cn
二、主要學術及社會兼職:
國家自然科學基金函審專家;
中國經濟林協會加工利用分會理事;
河北省食品學會青年工作委員會副秘書長;
國内外多家學術期刊審稿專家
九三學社農大二支社副主委
三、學習工作經曆
2001.9–2005.6,河北大學,生物技術專業,獲學士學位
2006.9–2008.6,南京農業大學,生物化學與分子生物學專業,獲碩士學位
2008.9–2011.6,南京農業大學,生物化學與分子生物學專業,獲博士學位
2007.9–2011.6,中國農業科學院油料作物研究所,客座研究生
2011.8–至今,bevictor伟德官网生物工程系主任、副教授、博士生導師、生物工程與釀酒工程專業負責人
2016.12-2017.9,美國Cleveland Clinic,博士後
四、主講課程及主要研究方向
1、主講課程:發酵工程與設備、發酵工藝學、生物制藥、微生物學、基因組學與轉錄組學等本科及研究生課程。
2、主要研究方向:益生菌資源開發利用與功能性食品研究;發酵食品功能性成分分析與人體健康研究;轉基因食品安全與風險交流研究。
五、主要研究成果、近年承擔的科研項目及獲獎情況:
主持項目:
國家自然科學基金(31301520)
河北省自然科學基金(C2016204129)
河北省科技計劃項目(12222904)
河北省高等學校科學技術研究項目(ZD2021059;QN2014065)
bevictor伟德官网青年科學基金(QJ201221)
參與項目:
國家自然科學基金(31601462)
國家自然科學基金(31501417)
國家自然科學基金(主任基金)(31140065)
國家自然科學基金面上項目(30671312)
國家重大科技專項/重大項目(2019ZX08015002-007)
國家重點研發計劃項目子課題(2017YFC1600901)
河北省重點研發計劃項目(20327112D;19227134D)
河北省自然科學基金(C2012204099)
河北省科技計劃項目(13222806)
中央級公益性科研院所基本科研業務費專項資金(20065049)
湖北省自然科學基金創新群體項目(2008CDA083)
石家莊市科學技術研究與發展計劃(11117272A)
發明專利:
申請和授權國家發明專利16項
六、代表性論文
發表論文60餘篇,其中SCI/EI收錄40餘篇,部分代表性論文如下:
[1] Copper inhibits postacidification of yogurt and affects its flavor: A study based on the Cop operon[J]. Journal of Dairy Science, 2023, 106(2):897-911.(Corresponding author)
[2] Effect of fructooligosaccharides on the colonization of Lactobacillus rhamnosus AS1.2466T in the gut of mice. Food Science and Human Wellness, 2023, 12(2):607-613.(Corresponding author)
[3] A novel endophytic bacterial strain improves potato storage characteristics by degrading glycoalkaloids and regulating microbiota. Postharvest Biology and Technology, 2023, 196:112176.(co-first author)
[4] Niacin inhibits post-acidification of yogurt based on the mining of LDB_RS00370 biomarker gene[J]. Food Research International, 2022, 162(Pt A):111929.(Corresponding author)
[5] Mechanism of gastrointestinal adaptability and antioxidant function of infant-derived Lactobacillus plantarum BF_15 through genomics. Food Science and Biotechnology, 2022, 31(11):1451-1462.(Corresponding author)
[6] Global transcriptomic analysis ofLactobacillus delbrueckiisubsp.bulgaricusATCC11842 reveals the role ofLDB_RS05285in the post-acidification of yogurt,Food & Function,Food & Function, 2021, 12(19):9077-9086.(Correspondingauthor)
[7] Probiotics, prebiotics, and synbiotics regulate the intestinal microbiota differentially and restore the relative abundance of specific gut microorganisms, Journal of Dairy Science, 2020, 103: 5816-5829.(first author)
[8] Colonization and immunoregulation of Lactobacillus plantarum BF_15, a novel probiotic strain from the feces of breast-fed infants, Food & Function, 2020, 11:3156-3166.(co-first author)
[9] Food-grade expression of nattokinase in Lactobacillus delbrueckii subsp. bulgaricus and its thrombolytic activity in vitro,BiotechnologyLetters,2020,42:2179–2187.(first author)
[10] Adhesion and Colonization of the Probiotic Lactobacillus rhamnosus Labeled by Dsred2 in Mouse Gut. Current Microbiology, 2019, 76:896-903.(first author)
[11]Induction of telomere-mediated chromosomal truncation and behavior of truncated chromosomes inBrassica napus. The Plant Journal, 2017, 91(4):700-713.(co-first author)
[12] Development of an antibiotic-free plasmid selection system based on thymine auxotrophy inLactococcus lactis. Annals of Microbiology. 2015, 65:1049-1055(first author)
[13] Construction ofLactococcus lactisthyA-null using Red recombination system. Annals of Microbiology. 2013, 63:951-956.(co-first author)
[14] Gene expression profiling ofSinapis albaleaves under drought stress and rewatering growth conditions with Illumina deep sequencing.Molecular Biology Reports. 2012, 39(5):5851-5857.(co-first author)
[15] Large-scale sequencing of normalized full-length cDNA library of soybean seed at different developmental stages and analysis of the gene expression profiles based on ESTs. Molecular Biology Reports. 2012, 39(3):2867-2874.(co-first author)
[16]Cloning, identification and characterization of a repetitive sequence flanking telomere and homologous tocanrepinBrassica napus.Botanical Studies,2010,51: 421-430.(first author)